EFFECTS OF NITRIC OXIDE ON ELABORATION OF SENSITIZATION IN HELIX POMATIA

Abstract: 

It was found that a preliminary injection of either NО-syntase inhibitor L-Name or the donor of nitroglyc-erine didn't prevent long-term sensitization but decreased it's intensity. Regular injection of nitroglycerine has no effect on membrane potential of multiple units during long term sensitization, and injection of L-Name decreases threshold potential which demonstrates the increase of neurons' excitability and corre-lates with the hyper-reaction of pneumostone.

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